Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans.
BackgroundBetaine (trimethylglycine) lowers plasma homocysteine, a possible risk factor for cardiovascular disease.However, studies in renal patients and in obese individuals who are on a weight-loss diet suggest that betaine supplementation raises blood cholesterol; data in healthy individuals are lacking.Such an effect on cholesterol would counte